Title:
更年期障害関連症候群の治療
Document Type and Number:
Japanese Patent JP5721322
Kind Code:
B2
Abstract:
Described are estradiol-containing pharmaceutical compositions and, and methods using the same to alleviate menopause-related symptoms, such as hot flushes, by topically administering estradiol at low effective doses.
Inventors:
John Brennan
Are Suns
Rex houghton
Zlove Bevia
Are Suns
Rex houghton
Zlove Bevia
Application Number:
JP2009504848A
Publication Date:
May 20, 2015
Filing Date:
April 13, 2007
Export Citation:
Assignee:
Bezan Healthcare Luxembourg S.A.
International Classes:
A61K9/06; A61K31/565; A61K47/10; A61K47/32; A61P15/12
Domestic Patent References:
| JP1072351A | ||||
| JP2004524354A | ||||
| JP2001523722A | ||||
| JP2005515964A |
Foreign References:
| WO2004080413A2 | ||||
| WO2005011618A2 |
Other References:
BRENNAN,J.J.et al,Serum concentrations of 17beta-estradiol and estrone after multiple-dose administration of percutaneous estradiol gel in symptomatic menopausal women,Ther Drug Monit,2001,Vol.23,No.2,p.134-138
Attorney, Agent or Firm:
Yasuhiko Murayama
Masatake Shiga
Takashi Watanabe
Shinya Mitsuhiro
Masatake Shiga
Takashi Watanabe
Shinya Mitsuhiro