Title:
アミノイミダゾールカルボキサミドの塩による腫瘍の治療および阻止
Document Type and Number:
Japanese Patent JP4842286
Kind Code:
B2
Abstract:
Compositions and methods are described for the induction of apoptosis inhibition of DNA synthesis, and/or inhibiting COX-2 activity using an effective amount of salts of aminoimidazole carboxamide, 5 amino 1,2,3-triazoles or a combination of salts thereof.
Inventors:
Veilmann felix
Application Number:
JP2008027656A
Publication Date:
December 21, 2011
Filing Date:
February 07, 2008
Export Citation:
Assignee:
Tactical Therapeutics, Inc.
International Classes:
A61K31/4164; A61K31/00; C07D249/04; A61K31/41; A61K31/415; A61K31/4192; A61K38/00; A61K38/19; A61K38/20; A61K38/21; A61K38/22; A61P15/00; A61P17/00; A61P17/06; A61P19/00; A61P19/02; A61P35/00; A61P35/02; A61P35/04; A61P43/00; C07D233/88; C07D233/90
Other References:
MANDEL,H.G. et al,The effect of 4-amino-5-imidazolecarboxamide on the carcinostatic action of 8-azaguanine,Cancer Res,1954年,Vol.14, No.11,p.808-11
NISHIO,H. et al,Mechanism of potentiation of the carcinostatic activity of 8-aza-guanine by 4(or 5)-aminoimidazole-5(or 4)-carboxamide analogs,Chem Pharm Bull (Tokyo),1969年,Vol.17, No.3,p.539-43
NISHIO,H. et al,Mechanism of potentiation of the carcinostatic activity of 8-aza-guanine by 4(or 5)-aminoimidazole-5(or 4)-carboxamide analogs,Chem Pharm Bull (Tokyo),1969年,Vol.17, No.3,p.539-43
Attorney, Agent or Firm:
Sadao Kumakura
Nobuo Ogawa
Atsushi Hakoda
Kenji Asai
Koji Hirayama
Nobuo Ogawa
Atsushi Hakoda
Kenji Asai
Koji Hirayama