Title:
TREPROSTINIL DERIVATIVES AND COMPOSITIONS AND USES THEREOF
Document Type and Number:
Japanese Patent JP2022003057
Kind Code:
A
Abstract:
To provide treprostinil derivatives that can act as prodrugs of treprostinil.SOLUTION: The present invention discloses a compound of formula (I), or a pharmaceutically acceptable salt thereof or the like (where R1 and R2 are independently hydrogen, alkylcarbonyl, alkoxyalkylcarbonyl or the like, where, both R1 and R2 are not hydrogen, and neither -OR1 nor -OR2 form acetate, benzoate or the like).SELECTED DRAWING: None
Inventors:
ZHANG XIAOMING
MEENAKSHI S VENKATRAMAN
CYRUS K BECKER
MEENAKSHI S VENKATRAMAN
CYRUS K BECKER
Application Number:
JP2021151659A
Publication Date:
January 11, 2022
Filing Date:
September 17, 2021
Export Citation:
Assignee:
CORSAIR PHARMA INC
International Classes:
C07C69/30; A61K9/70; A61K31/215; A61K31/216; A61K31/222; A61K31/265; A61K31/337; A61K31/341; A61K31/351; A61P9/04; A61P9/10; A61P9/12; A61P11/00; A61P11/06; A61P13/12; A61P17/02; A61P25/04; A61P29/02; A61P35/00; A61P37/04; A61P43/00; C07C69/67; C07C69/708; C07C69/712; C07C69/74; C07C69/75; C07C69/96; C07D305/08; C07D307/24; C07D309/08
Domestic Patent References:
| JP2003523935A | 2003-08-12 | |||
| JP2014527050A | 2014-10-09 | |||
| JP2007501281A | 2007-01-25 | |||
| JP2003535132A | 2003-11-25 |
Foreign References:
| WO2014110491A1 | 2014-07-17 | |||
| WO2003049676A2 | 2003-06-19 |
Attorney, Agent or Firm:
Hatsushi Shimizu
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Hideki Kodera
Masato Ozeki
Kazuya Kawamoto
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Hideki Kodera
Masato Ozeki
Kazuya Kawamoto