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Title:
TREPROSTINIL TREATMENT FOR INTERSTITIAL LUNG DISEASE AND ASTHMA
Document Type and Number:
Japanese Patent JP2013189459
Kind Code:
A
Abstract:

To provide a method for treatment or prevention of interstitial lung disease, asthma, condition related to the interstitial lung disease such as fibroid lung, or condition related to the asthma.

Treprostinil, its delivative, or a pharmaceutically acceptable salt thereof is used. The delivative may be an acid delivative of treprostinil, a prodrug of treprostinil, an extended-release form of treprostinil, an inhaler form of treprostinil, an oral form of treprostinil, a polymorph form of treprostinil, or an isomeric form of preprostinil. Administration can be executed in dosage forms suitable for intravenous dosing and oral dosing chosen from a group of tablets and capsules. Effective amount is at least 1.0ng/kg (body weight)/min.


Inventors:
WADE MICHAEL
RICH STUART
SULLIVAN EUGENE
ROSCIGNO ROBERT
JEFFS ROGER
Application Number:
JP2013116923A
Publication Date:
September 26, 2013
Filing Date:
June 03, 2013
Export Citation:
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Assignee:
UNITED THERAPEUTICS CORP
International Classes:
A61K31/192; A61K9/12; A61K9/20; A61K9/48; A61K9/72; A61P11/00; A61P11/06; A61P19/04; A61P29/00
Domestic Patent References:
JPH0240325A1990-02-09
Other References:
JPN6014029757; Barst,R.J.,et al.: '"Long-term outcome in pulmonary arterial hypertension patients treated with subcutaneous treprostin' Eur. Respir. J. Vol.28,No.6, 20061201, P.1195-1203
JPN6014029758; 嶋田博光 外6名: 'P-II-E12"原発性肺高血圧の治療過程における6分間歩行テストの有用性"' 日本小児循環器学会雑誌 Vol.20,No.3, 20040501, P.405
JPN6014029759; 坂巻文雄: '私の処方"肺動脈性肺高血圧症の薬物療法"' Modern Physician Vol.26,No.6, 200606, P.1028-1029
JPN6014029760; 佐藤徹: '特集 肺高血圧症を診る;識る 5"その他の評価法(BNP,UA,6MW)"' Heart View Vol.10,No.8, 200608, P.892-897
Attorney, Agent or Firm:
Shinjiro Ono
Yasushi Kobayashi
Shigeo Takeuchi
Osamu Yamamoto
Takumi Terachi