Title:
治療に有用なトリアゾール化合物
Document Type and Number:
Japanese Patent JP4033886
Kind Code:
B2
Abstract:
A compound of formula (I), or a pharmaceutically acceptable derivative thereof, wherein V represents -(CH)(O)-, -CO-, or -CH(Calkyl)-; W is -0-, -S(O), or -N(R)-Rrepresents H, Calkyl, (CH)COR, CO(CH)NRR, SOR, (CH)OR, (CH),NRR, or (CH)het; hetrepresents a saturated or unsaturated heterocycle of from 3 to 8 atoms containing one or more heteroatoms selected from O, N, or S, optionally substituted with Calkyl; X and Y independently represent H, Calkyl, halogen, OH, CF, OCF, OR; Z represents -(CH)(O), -CO- or -CH(Calkyl)-; Ring A represents a 4-7 membered, saturated N-containing heterocycle, optionally substituted with OH, and in which optionally at least one ring N is substituted with O; Ring B represents phenyl or a 4-7 membered unsaturated N-containing heterocycle, optionally substituted with OH, halogen, CN, CONH, CF, OCF, and in which optionally at least one ring N is substituted with O; Rand Rindependently represent H, Calkyl [optionally substituted with OH, halogen, N(Calkyl), or Calkyloxy], Calkyloxy, N(Calkyl), or [Ccycloalkyl]; or Rand R, together with the nitrogen atom to which they are attached independently represent a heterocycle of from 3 to 8 atoms, optionally substituted with Calkyl; Rrepresents straight or branched Calkyl, a and c independently represent 0, 1, or 2; b, e and g independently represent 0 or 1; d and f independently represent 1 or 2;are useful in the treatment of dysmenorrhoea.
Inventors:
Brian's, Justin Steven
Johnson, Patrick Stephen
Rachel Jane, Russell
Rickmans, Thomas
Stove, Alan
Wayman, Christopher Peter
Johnson, Patrick Stephen
Rachel Jane, Russell
Rickmans, Thomas
Stove, Alan
Wayman, Christopher Peter
Application Number:
JP2006500323A
Publication Date:
January 16, 2008
Filing Date:
February 09, 2004
Export Citation:
Assignee:
Pfizer Inc.
International Classes:
C07D487/04; A61K31/41; A61K31/4196; A61K31/4427; A61K31/4545; A61K31/501; A61K31/55; A61K31/5517; A61K31/553; A61K31/554; A61P1/04; A61P1/08; A61P1/14; A61P3/04; A61P3/10; A61P3/12; A61P7/02; A61P7/10; A61P9/00; A61P9/04; A61P9/10; A61P9/12; A61P11/02; A61P11/06; A61P13/02; A61P13/12; A61P15/06; A61P15/08; A61P15/10; A61P15/12; A61P25/00; A61P25/20; A61P25/22; A61P25/24; A61P25/28; A61P27/02; A61P27/06; A61P27/14; A61P29/00; A61P31/04; A61P35/00; A61P43/00; C07D243/00; C07D249/00; C07D267/00; C07D401/04; C07D413/14; C07D498/04; C07D513/04; A61K; A61P; C07D
Foreign References:
| WO2002083678A1 |
Attorney, Agent or Firm:
Kazuo Shamoto
Shinjiro Ono
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
Akiko Yamaguchi
Shinjiro Ono
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
Akiko Yamaguchi