トリアゾール由来キナーゼインヒビターおよびその使用

Japanese Patent JP2004532234

A

Described herein are compounds that are useful as protein kinase inhibitors having the formula: where Ht, R², T, and m are as described in the specification. The compounds are useful for treating diseases in mammals that are alleviated by a protein kinase inhibitor, particularly diseases such as cancer, inflammatory disorders, restenosis, and cardiovascular disease.

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Hale, Michael Robin
Francois, Maltais

JP2002585399A

October 21, 2004

April 26, 2002

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VERTEX PHARMACEUTICALS INCORPORATED

A61K31/4192; A61K31/4196; A61K31/428; A61K31/4439; A61K31/506; A61K31/5377; A61K45/00; A61P1/16; A61P3/10; A61P5/00; A61P7/02; A61P9/00; A61P9/04; A61P9/10; A61P11/00; A61P17/06; A61P19/08; A61P21/00; A61P25/00; A61P25/08; A61P25/14; A61P25/16; A61P25/28; A61P29/00; A61P31/04; A61P31/12; A61P35/00; A61P35/02; A61P37/04; A61P37/06; A61P37/08; A61P43/00; C07D249/06; C07D249/08; C07D249/10; C07D401/14; C07D403/04; C07D403/14; C07D405/14; C07D417/14; C07D521/00; (IPC1-7): C07D249/06; A61K31/4192; A61K31/4196; A61K31/428; A61K31/4439; A61K31/506; A61K31/5377; A61K45/00; A61P1/16; A61P3/10; A61P5/00; A61P7/02; A61P9/00; A61P9/04; A61P9/10; A61P11/00; A61P17/06; A61P19/08; A61P21/00; A61P25/00; A61P25/08; A61P25/14; A61P25/16; A61P25/28; A61P29/00; A61P31/04; A61P31/12; A61P35/00; A61P35/02; A61P37/04; A61P37/06; A61P37/08; A61P43/00; C07D249/08; C07D401/14; C07D403/04; C07D403/14; C07D405/14; C07D417/14

Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita

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