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Title:
TRIAZOLOPYRIDINE COMPOUND, AND ACTION AS PROLYL HYDROXYLASE INHIBITOR AND ERYTHLOPOIETIN PRODUCTION INDUCER THEREOF
Document Type and Number:
Japanese Patent JP2015003933
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide a triazolopyridine compound having prolyl hydroxylase inhibitory action and erythlopoietin production-inducing potency.SOLUTION: The present invention is related to a compound represented by the following general formula [I] (each symbol in the formula is defined as in the specification), its pharmaceutically acceptable salt or its solvate, and a prolyl hydroxylase inhibitor and an erythlopoietin production inducer containing the compound. The compound of the present invention exhibits prolyl hydroxylase inhibitory action and erythlopoietin production inducing potency, and is useful as a preventive or therapeutic agent of various kinds of diseases and disease states (disorders) caused by reduction of erythlopoietin production.

Inventors:
MITANI IKUO
IKUKOSHI YOSUKE
MATSUI TAKUYA
YOKOTA MASAHIRO
TERASHITA MASAKAZU
MOTODA DAI
KAMIYAMA KAZUTO
ABE HIROYUKI
HOTTA TAKAHIRO
ITO TAKASHI
Application Number:
JP2014207896A
Publication Date:
January 08, 2015
Filing Date:
October 09, 2014
Export Citation:
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Assignee:
JAPAN TOBACCO INC
International Classes:
C07D471/04; A61K31/437; A61P5/00; A61P7/06; A61P43/00
Domestic Patent References:
JP5021797B22012-09-12
JPH11302257A1999-11-02
Foreign References:
WO2007136990A22007-11-29
WO2007103905A22007-09-13
WO2008130600A22008-10-30
WO2008089052A22008-07-24
WO2007015011A22007-02-08
Attorney, Agent or Firm:
Takashima 1
Kyoko Doi
Kamata 光宜
Tamura Yasaka child
Murata Miyuki
Koike 順造
Hirofumi Toma