Title:
TRITERPENE SAPONIN SYNTHESIS, INTERMEDIATES, AND ADJUVANT COMBINATIONS
Document Type and Number:
Japanese Patent JP2022169763
Kind Code:
A
Abstract:
To provide triterpene glycoside saponin-derived adjuvants, syntheses thereof, and intermediates thereto, and also provide pharmaceutical compositions comprising compounds of the present invention and methods of using the compounds or compositions in the treatment of and immunization for infectious diseases.SOLUTION: Provided are compounds that are analogs of QS-21 and QS-7, for example having the following structure.SELECTED DRAWING: Figure 1
Inventors:
Chan Amanda
Gardner Jeffrey
Nordstrom Lars
Warcowich William
Martin Jay Tyler
Chan Wei Don
Gardner Jeffrey
Nordstrom Lars
Warcowich William
Martin Jay Tyler
Chan Wei Don
Application Number:
JP2022137656A
Publication Date:
November 09, 2022
Filing Date:
August 31, 2022
Export Citation:
Assignee:
Adjuvance Technologies, Inc.
International Classes:
C07H15/256; A61K31/704; A61K36/36; A61K39/02; A61K39/05; A61K39/08; A61K39/09; A61K39/10; A61K39/29; A61K39/39; A61P31/04; A61P31/20; A61P37/04; A61P43/00; C07C51/47; C07C62/36; C07H15/04; C07H15/18
Attorney, Agent or Firm:
Esaki Mitsufumi
Blacksmith Minoru Sawa
Katsuri Uenishi
Ichiro Torayama
Ishida Taisei
Blacksmith Minoru Sawa
Katsuri Uenishi
Ichiro Torayama
Ishida Taisei