Title:
TRITIUM-LABELLED RADIOACTIVE ESTRADIENE DERIVATIVES, MANUFACTURE, INTERMEDIATES, EXAMINATION OF STEROID IN VIVO STREAM AND USE FOR RADIOIMMUNODETERMINATION
Document Type and Number:
Japanese Patent JPS6034989
Kind Code:
A
Abstract:
Novel radioactive estradienes labelled with tritium of the formula I wherein 3H is tritium and R is selected from the group consisting of hydrogen, alkyl of 1 to 6 carbon atoms and acyl of an organic carboxylic acid of 1 to 10 carbon atoms and the study and radioimmunological determination of non-radioactive 11 beta -(4-dimethylaminophenyl)-17 alpha -(prop-1-ynyl)- DELTA 4,9-estradiene-17 beta -ol-3-one and its metabolites in biological fluids and novel intermediates.
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Inventors:
ARAN JIYUKE
JIYAN NOERU BERUTSU
JIYAN SARUMON
MISHIERU MUURAN
JIYAN NOERU BERUTSU
JIYAN SARUMON
MISHIERU MUURAN
Application Number:
JP12090084A
Publication Date:
February 22, 1985
Filing Date:
June 14, 1984
Export Citation:
Assignee:
ROUSSEL UCLAF
International Classes:
A61K51/00; A61K51/04; C07B59/00; G01N33/53; C07J1/00; C07J9/00; C07J21/00; C07J41/00; C07J43/00; G01N33/534; G01N33/74; (IPC1-7): A61K49/02; C07J9/00; G01N33/534
Attorney, Agent or Firm:
Motohiro Kurauchi