Title:
Trk prevention compound
Document Type and Number:
Japanese Patent JP6160613
Kind Code:
B2
Abstract:
An object of the present invention is to provide a drug containing a compound having Trk-inhibiting activity as an active ingredient in prophylaxis and/or therapy of diseases such as pain, pruritus, lower urinary tract dysfunction, asthma, allergic rhinitis, inflammatory bowel disease or Chagas disease. A compound represented by the general formula (I) :
(wherein all symbols represent the same meanings as described in the specification), a salt thereof, an N-oxide thereof, a solvate thereof or a prodrug thereof is useful as a drug component having Trk-inhibiting activity in prophylaxis and/or therapy of diseases such as pain, pruritus, lower urinary tract dysfunction, asthma, allergic rhinitis, inflammatory bowel disease or Chagas disease.
Inventors:
Atsushi Takeuchi
Ikura Seiyasu
Katsuhito Higashino
Maki Iwahashi
Hayamura Keiya
Ikura Seiyasu
Katsuhito Higashino
Maki Iwahashi
Hayamura Keiya
Application Number:
JP2014512670A
Publication Date:
July 12, 2017
Filing Date:
April 25, 2013
Export Citation:
Assignee:
Ono Pharmaceutical Co., Ltd.
International Classes:
C07D417/14; A61K31/444; A61K31/506; A61K31/5377; A61K31/55; A61P1/04; A61P11/02; A61P11/06; A61P13/02; A61P17/04; A61P25/04; A61P33/02; A61P37/08; A61P43/00; C07D417/12
Domestic Patent References:
| JP2008528585A | ||||
| JP2009518298A | ||||
| JP2011502160A |
Foreign References:
| WO2003068228A1 | ||||
| WO2007076473A2 | ||||
| WO2008131276A1 | ||||
| WO2008131227A1 |
Attorney, Agent or Firm:
Patent Business Corporation Saegusa International Patent Office
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