Title:
腫瘍タンパク質のプロテインキナーゼ
Document Type and Number:
Japanese Patent JP3745558
Kind Code:
B2
Abstract:
An isolated polypeptide (JNK) characterized by having a molecular weight of 46 kD or 55 kD as determined by reducing SDS-PAGE, having serine and theonine kinase activity, phosphorylating the c-Jun N-terminal activation domain and polynucleotide sequences and method of detection of JNK are provided herein. JNK phosphorylates c-Jun N-terminal activation domain which affects gene expression from AP-1 sites.
Inventors:
Karin, Michael
Crack, Masahiko
Phosphorus, anine
Crack, Masahiko
Phosphorus, anine
Application Number:
JP13932999A
Publication Date:
February 15, 2006
Filing Date:
May 19, 1999
Export Citation:
Assignee:
The Regents of The University of California
International Classes:
C12N9/12; A61K31/00; G01N33/573; A61K38/00; A61K39/395; A61P5/40; A61P9/08; A61P9/10; A61P25/04; A61P29/00; A61P31/00; A61P31/12; A61P35/00; A61P35/02; A61P37/00; A61P37/02; A61P43/00; C07H21/04; C07K14/705; C07K14/82; C07K16/30; C07K16/32; C07K16/40; C12N5/10; C12N15/02; C12N15/09; C12N15/54; C12P21/08; C12Q1/02; C12Q1/48; C12Q1/68; G01N33/574; G01N33/577
Attorney, Agent or Firm:
Atsushi Nakajima
Kato Kazunori
Katsuichi Nishimoto
Kato Kazunori
Katsuichi Nishimoto