Title:
チロシンキナーゼ阻害剤
Document Type and Number:
Japanese Patent JP2013514973
Kind Code:
A
Abstract:
The present invention relates to pyridazin-4(1H)-one derivatives, that are useful for treating cellular proliferative diseases, for treating disorders associated with MET activity, and for inhibiting the receptor tyrosine kinase MET. The invention also related to compositions which comprise these compounds, and methods of using them to treat cancer in mammals.
Inventors:
Young, Jyonathan
Chiyako, Barbara
Altman, michael
Guerin, David
Martinez, Mitsushiel
Ribkin, alexie
Wilson, Kevin
Lip odo, Kyasarin
White, kaysalin
Sirday, laura
Chichietsu, Stephanie
Daniel, Machine H
Ahern, Sheen Pee
Hualucon, daniel
Oshinboni, Ekundayo
Chiyako, Barbara
Altman, michael
Guerin, David
Martinez, Mitsushiel
Ribkin, alexie
Wilson, Kevin
Lip odo, Kyasarin
White, kaysalin
Sirday, laura
Chichietsu, Stephanie
Daniel, Machine H
Ahern, Sheen Pee
Hualucon, daniel
Oshinboni, Ekundayo
Application Number:
JP2012544691A
Publication Date:
May 02, 2013
Filing Date:
December 14, 2010
Export Citation:
Assignee:
Merck Sharp End Dome Corporation
International Classes:
C07D237/14; A61K31/50; A61K31/501; A61K31/506; A61K31/5377; A61K31/541; A61P9/00; A61P29/00; A61P35/00; A61P37/00; A61P43/00; C07D401/04; C07D401/06; C07D401/10; C07D401/12; C07D401/14; C07D403/04; C07D403/10; C07D403/12; C07D403/14; C07D405/12; C07D405/14; C07D413/12; C07D413/14; C07D417/14; C07D471/04
Attorney, Agent or Firm:
Yoshikazu Iwase
Makoto Ono
Kenkyo Kanayama
Mitsuaki Tsubokura
Kazuki Shigemori
Kenji Ando
Yasufumi Shiroyama
Makoto Ono
Kenkyo Kanayama
Mitsuaki Tsubokura
Kazuki Shigemori
Kenji Ando
Yasufumi Shiroyama