Title:
ユビキチン化－プロテアソーム系に関連する化合物および薬学的組成物
Document Type and Number:
Japanese Patent JP7017787
Kind Code:
B2
Abstract:
The invention relates to new compounds with low cytotoxicity for blocking ubiquitination-proteasome system in diseases. Accordingly, these compounds can be used in treatment of treating disorders including, but not limited to, cancers, neurodegenerative diseases, inflammatory disorders and autoimmune disorders and metabolic disorders.
Inventors:
Yen, Yun
Riu, Jin-Pin
Bread, Shiou-Rin
Riu, Jin-Pin
Bread, Shiou-Rin
Application Number:
JP2018504151A
Publication Date:
February 09, 2022
Filing Date:
July 30, 2016
Export Citation:
Assignee:
Calgent Biotechnology Company, Limited
International Classes:
C07C237/34; A61K31/136; A61K31/166; A61K31/18; A61K31/40; A61K31/4045; A61K31/4409; A61K31/4453; A61K31/47; A61K31/5375; A61K33/243; A61K45/00; A61P3/00; A61P3/02; A61P3/06; A61P3/10; A61P9/10; A61P17/06; A61P19/02; A61P25/14; A61P25/28; A61P29/00; A61P31/00; A61P31/12; A61P35/00; A61P35/02; A61P37/02; A61P43/00; C07D209/04; C07D209/14; C07D209/44; C07D213/40; C07D215/38; C07D295/13
Foreign References:
| WO1997030022A1 | ||||
| KR1020130101908A | ||||
| US20110201609 | ||||
| US20130071353 | ||||
| US20030186948 |
Other References:
European Journal of Medicinal Chemistry,2014年,84,p.247-263
Bioorganic & Medicinal Chemistry,2010年,18(15),p.5576-5592
Bioorganic & Medicinal Chemistry,2010年,18(15),p.5576-5592
Attorney, Agent or Firm:
Shusaku Yamamoto
Morishita Natsuki
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto
Morishita Natsuki
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto