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Title:
UNIT DOSAGE, AEROSOL, KIT, AND METHOD FOR TREATING CARDIAC DISEASE BY TRANSPULMONARY ADMINISTRATION
Document Type and Number:
Japanese Patent JP2017160268
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide a unit dosage, aerosol, a kit, and a method for treating a cardiac disease by transpulmonary administration.SOLUTION: A method for treating atrial arrhythmia includes administering an effective dose of at least one antiarrhythmic pharmaceutical agent to a patient who needs it, and the at least one antiarrhythmic pharmaceutical agent passes through pulmonary veins first to enter a heart, and reaches a left atrium. Another method for treating atrial arrhythmia includes administering an effective dose of at least one antiarrhythmic pharmaceutical agent to a patient who needs it by inhalation. An amount of the at least one antiarrhythmic pharmaceutical agent can reach a peak in a coronary sinus of a heart at the point of the range of 10 seconds to 30 seconds from start of administration. A unit dosage, aerosol, and a kit are also taken in consideration.SELECTED DRAWING: None

Inventors:
CARLOS A SCHULER
RANGACHARI NARASIMHAN
Application Number:
JP2017123029A
Publication Date:
September 14, 2017
Filing Date:
June 23, 2017
Export Citation:
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Assignee:
INCARDA THERAPEUTICS INC
International Classes:
A61K45/00; A61K31/138; A61K31/165; A61K31/166; A61K31/167; A61K31/18; A61K31/216; A61K31/343; A61K31/4166; A61K31/4402; A61K31/4422; A61K31/4439; A61K31/4458; A61K31/49; A61K31/5377; A61K31/554; A61K31/704; A61K31/7076; A61K47/02; A61K47/06; A61K47/12; A61P9/06
Domestic Patent References:
JP2002529393A2002-09-10
JP2004510731A2004-04-08
JPH11222424A1999-08-17
Other References:
EUR.RESPIR.REV., vol. 10, no. 72, JPN6016024321, 2000, pages 210 - 212, ISSN: 0004005026
タンボコール(登録商標)錠50MG タンボコール(登録商標)100MG 添付文書, JPN6018019954, October 2011 (2011-10-01), pages 1 - 6, ISSN: 0004005027
PREHOSPITAL EMERGENCY CARE, vol. 1, no. 4, JPN6016024323, 1997, pages 227 - 232, ISSN: 0003807401
AM.J.EMERG.MED., vol. 19, no. 1, JPN6016024325, 2001, pages 6 - 9, ISSN: 0003807402
Attorney, Agent or Firm:
Hidesaku Yamamoto
Natsuki Morishita
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto