経肺投与によって心疾患を治療するための単位用量、エアロゾル、キット、および方法

Japanese Patent JP7071949

B2

Methods of treating atrial arrhythmia include administering an effective amount of at least one antiarrhythmic pharmaceutical agent to a patient in need thereof, such that the at least one antiarrhythmic pharmaceutical agent first enters the heart through the pulmonary vein to the left atrium. Other methods of treating atrial arrhythmia include administering by inhalation an effective amount of at least one antiarrhythmic pharmaceutical agent to a patient in need thereof. An amount of the at least one antiarrhythmic pharmaceutical agent may peak in the coronary sinus of the heart at a time ranging from 10 seconds to 30 minutes from initiation of the administering. Unit doses, aerosols, and kits are also contemplated.

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WO/2005/044192	TRIAZOLE COMPOUNDS AND USES RELATED THERETO
JP3905573	SUBSTITUTED BENZENESULFONYLUREA AND-THIOUREA, THEIR PREPARATION AND THEIR USE FOR PHARMACEUTICAL PREPARATION BASED ON THE COMPOUNDS, AND MBDICAMENT CONTAINING THEM

Carlos A. Schuller
Langachari Narashiman

JP2019162836A

May 19, 2022

September 06, 2019

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Incarda Therapeutics, Incorporated

A61K31/18; A61K9/08; A61K9/12; A61K9/72; A61K31/4458; A61K31/554; A61K47/08; A61K47/12; A61K47/40; A61P9/06

JP2002529393A

Eur. Respir. Rev., (2000), 10, [72], p.210-212

Shusaku Yamamoto
Morishita Natsuki
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto

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