UREA DERIVATIVE

Japanese Patent JP2003192587

A

To provide a medicine having excellent activity as a VR1 antagonist and useful for the prevention and treatment of diseases relating to VR1 activity, especially the treatment of urgency incontinence, overactive bladder, chronic pain, neuropathic pain, postoperative pain, chronic rheumatic pain, neuralgia, neuropathy, hyperalgesia, nerve damage, ischemia, neurodegeneration, stroke, incontinence and/or inflammatory diseases.

The medicine contains a urea derivative or its salt as an active component.

YURA TAKESHI
MOGI MUNEHITO
IKEGAMI YUKA
MASUDA TSUTOMU
KOKUBO TOSHIO
URBAHNS KLAUS
YOSHIDA NAGAHIRO
MARUMO MAKIKO
SHIROO MASAHIRO
TAJIMI MASAOMI
TAKESHITA KEISUKE
MORIWAKI TOSHIYA
TSUKIMI YASUHIRO

JP2001395031A

July 09, 2003

December 26, 2001

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BAYER AG

A61K31/343; A61K31/365; A61K31/381; A61K31/404; A61K31/416; A61K31/4184; A61K31/4192; A61K31/428; A61P9/00; A61P9/10; A61P13/02; A61P13/10; A61P19/02; A61P25/00; A61P25/02; A61P25/04; A61P25/18; A61P25/28; A61P29/00; A61P43/00; C07D209/08; C07D231/56; C07D235/06; C07D235/08; C07D235/10; C07D249/18; C07D277/62; C07D277/64; C07D277/70; C07D277/72; C07D277/74; C07D307/83; C07D307/88; C07D333/54; (IPC1-7): A61K31/343; A61K31/381; A61K31/404; A61K31/416; A61K31/4184; A61K31/4192; A61K31/428; A61P9/00; A61P9/10; A61P13/02; A61P13/10; A61P19/02; A61P25/00; A61P25/02; A61P25/04; A61P25/28; A61P29/00; C07D209/08; C07D231/56; C07D235/08; C07D235/10; C07D249/18; C07D277/62; C07D277/64; C07D277/70; C07D277/74; C07D307/88; C07D333/54

Ikeuchi, Sato & Partners

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