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Title:
免疫系に関する疾病を治療するためのCRMPファミリーのタンパク質の使用
Document Type and Number:
Japanese Patent JP4499414
Kind Code:
B2
Abstract:
The invention concerns the use of at least a protein of the CRMP family, a polypeptide fragment or an active biological derivative thereof, a nucleotide sequence or sequence fragment coding for said protein, an antisense sequence capable of being specifically hybridized with a sequence with nucleotide-type encoding of said protein or an antibody directed against said protein for producing a medicine for treating diseases related to a dysfunction of the immune system. The invention also concerns a method for diagnosing an autoimmune pathology which consists in measuring the expression of a CRMP protein in the lymphocytes.

Inventors:
Giraudon, Pascal
Belin, Marie-Francoise
Marx, Christoph
Corus, Pierre
Antoine, Jean-Christophe
Onora, Jerome
Application Number:
JP2003526426A
Publication Date:
July 07, 2010
Filing Date:
September 09, 2002
Export Citation:
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Assignee:
Institut Nacional de la Santoue de la Leche Che Medical (ENS A/M)
International Classes:
G01N33/50; G01N33/53; A61K31/7088; A61K39/395; A61K48/00; A61P25/00; A61P25/28; A61P31/12; A61P31/14; A61P31/18; A61P31/22; A61P35/02; A61P37/00; C07K14/47; C12N1/00; C12N15/09; C12Q1/68; G01N33/15; G01N33/566
Domestic Patent References:
JP2001512971A
Foreign References:
FR2805540A1
Other References:
ANNALS OF NEUROLOGY,2001年 2月,Vol.49, No.2,P.146-154
Attorney, Agent or Firm:
Atsushi Aoki
Takashi Ishida
Fukumoto product
Tetsuji Koga
Kazuhiro Nakamura
Yoichi Watanabe
Masaru Nakajima