Title:
胆道ジスキネジーおよび/または胆道痛/不快の治療のためのGLP-1分子の使用
Document Type and Number:
Japanese Patent JP2009507050
Kind Code:
A
Abstract:
The present invention relates to molecules, compositions and methods suitable for the treatment or prevention of biliary dyskinesia and/or pain and/or discomfort originating from the biliary tree. The peptide hormone glucagon-like peptide-1 (GLP-1) has both anti-secretory effects and smooth muscle relaxatory properties in the gastrointestinal tract. GLP-1 exists in several forms, where the natural occurring GLP-1 molecules are GLP-1 (1-37), GLP-1 (7-37), and the amidated versions GLP-1 (1-36)amide, GLP-1 (7-36)amide. Other molecules capable of binding to and activating the GLP-1 receptor is herein included in the tern GLP-1 molecules. GLP-1 molecules may be naturally occurring or homologues of GLP-1 having one or more amino acid substitutions or modifications. The GLP-1 molecules are used for the manufacture of a medicament for the treatment or prevention of biliary dyskinesia and/or pain and/or discomfort originating from the biliary tree.
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Inventors:
Tina Geritz Nielsen
Henrik Nilsson
Christian Hansen
Hans Te Chambie
Henrik Nilsson
Christian Hansen
Hans Te Chambie
Application Number:
JP2008529470A
Publication Date:
February 19, 2009
Filing Date:
September 06, 2006
Export Citation:
Assignee:
Gastrotech Pharma A/S
International Classes:
A61K38/26; A61K31/167; A61K31/485; A61K31/60; A61K45/00; A61P1/16; A61P29/00; G01N33/15; G01N33/50
Attorney, Agent or Firm:
Kyousei Tamura
Samejima Mutsumi
Nagatoshi Shinagawa
Shinichiro Yamanaka
Samejima Mutsumi
Nagatoshi Shinagawa
Shinichiro Yamanaka