Title:
妊娠促進のためのＬＰＡの使用及び妊娠促進剤
Document Type and Number:
Japanese Patent JP5735918
Kind Code:
B2
Abstract:
The objective is to find compounds which have an activity to improve the success rate of pregnancy and implantation in blastocyst transfer in mammals, to provide a method of producing and using the compounds, and to provide a pregnancy-promoting agent. Disclosed is a pregnancy-promoting agent containing one or more lysophosphatidic acids selected from the group consisting of LPA-C16:0, LPA-C16:1, LPA-C18:0, LPA-C18:1 and LPA-C18:2.
Inventors:
Masahide Shiotani
Sakae Goto
Mitsuo Shimizu
Sakae Goto
Mitsuo Shimizu
Application Number:
JP2011528819A
Publication Date:
June 17, 2015
Filing Date:
August 25, 2010
Export Citation:
Assignee:
Masahide Shiotani
Sakae Goto
jcr pharma corporation
Sakae Goto
jcr pharma corporation
International Classes:
A61P15/08; A61K31/661
Foreign References:
| WO2008016039A1 | 2008-02-07 | |||
| WO2008016039A1 | 2008-02-07 |
Other References:
JPN6014035380; Ｈｕｍａｎ Ｒｅｐｒｏｄｕｃｔｉｏｎ ２２（Ｓｕｐｐｌ．１）, 2007, Ｉ２１１-Ｉ２１４
JPN6014035378; Ｂｉｏｌｏｇｙ ｏｆ Ｒｅｐｒｏｄｕｃｔｉｏｎ ７７（６）, 2007, ９５４-９５９
JPN6010063844; 徳村彰、他５名: '保温血漿および卵胞液に存在するリゾホスファチジン酸の生成機構' 脂質生化学研究 ３６, 1994, ２３-２６
JPN6014035382; Ｎａｔｕｒｅ ４３５（７０３８）, 2005, １０４-１０８
JPN6014035380; Ｈｕｍａｎ Ｒｅｐｒｏｄｕｃｔｉｏｎ ２２（Ｓｕｐｐｌ．１）, 2007, Ｉ２１１-Ｉ２１４
JPN6014035378; Ｂｉｏｌｏｇｙ ｏｆ Ｒｅｐｒｏｄｕｃｔｉｏｎ ７７（６）, 2007, ９５４-９５９
JPN6010063844; 徳村彰、他５名: '保温血漿および卵胞液に存在するリゾホスファチジン酸の生成機構' 脂質生化学研究 ３６, 1994, ２３-２６
JPN6014035382; Ｎａｔｕｒｅ ４３５（７０３８）, 2005, １０４-１０８
JPN6014035378; Ｂｉｏｌｏｇｙ ｏｆ Ｒｅｐｒｏｄｕｃｔｉｏｎ ７７（６）, 2007, ９５４-９５９
JPN6010063844; 徳村彰、他５名: '保温血漿および卵胞液に存在するリゾホスファチジン酸の生成機構' 脂質生化学研究 ３６, 1994, ２３-２６
JPN6014035382; Ｎａｔｕｒｅ ４３５（７０３８）, 2005, １０４-１０８
JPN6014035380; Ｈｕｍａｎ Ｒｅｐｒｏｄｕｃｔｉｏｎ ２２（Ｓｕｐｐｌ．１）, 2007, Ｉ２１１-Ｉ２１４
JPN6014035378; Ｂｉｏｌｏｇｙ ｏｆ Ｒｅｐｒｏｄｕｃｔｉｏｎ ７７（６）, 2007, ９５４-９５９
JPN6010063844; 徳村彰、他５名: '保温血漿および卵胞液に存在するリゾホスファチジン酸の生成機構' 脂質生化学研究 ３６, 1994, ２３-２６
JPN6014035382; Ｎａｔｕｒｅ ４３５（７０３８）, 2005, １０４-１０８
Attorney, Agent or Firm:
Takumi Hayasaka