USE OF ALPHA-2I SELECTIVE ADRENALIN RECEPTOR ACTIVE SUBSTANCE FOR MEMORY IMPROVEMENT

Title:

USE OF ALPHA-2I SELECTIVE ADRENALIN RECEPTOR ACTIVE SUBSTANCE FOR MEMORY IMPROVEMENT

Document Type and Number:

Japanese Patent JPS63183524

Kind Code:

A

Abstract:

Disclosed is a method of treating memory disorders and cognitive decline, e.g., age-related cognitive decline, in a primate by administering thereto a therapeutically effective amount of an alpha-2 agonist having a high affinity for the alpha-2I subtype, e.g., guanfacine and guanabenz or a nontoxic, pharmaceutically acceptable salt thereof. Particularly preferred is the use of alpha-2I selective agonists such as guanfacine.

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Inventors:

EIMI EFU TEII ANSUTEN
PATORISHIA ESU GOORUDOMANRAKIT

Application Number:

JP27198487A

Publication Date:

July 28, 1988

Filing Date:

October 29, 1987

Export Citation:

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Assignee:

UNIV YALE

International Classes:

A61K31/155; A61K31/165; A61P25/28; (IPC1-7): A61K31/155; A61K31/165; C07C129/12

Attorney, Agent or Firm:

Motohiro Kurauchi (1 outside)

Previous Patent: JPS63183523

Next Patent: REMEDY FOR ARRHYTHMIA