Title:
グラム陽性細菌及びマイコバクテリアの作用を阻止するための抗体の使用
Document Type and Number:
Japanese Patent JP3892902
Kind Code:
B2
Abstract:
The present invention concerns a method of treating bacteremia, sepsis and other forms of toxemia caused by Gram-positive bacteria and mycobacteria comprising administering a therapeutically effective amount of anti-CD14 antibody molecules. A therapeutic composition comprising anti-CD14 antibody molecules in a pharmaceutically acceptable excipient is also contemplated.
Inventors:
Ulevich, Richard Jay.
Tobias, Peter S.
Pugin, jerome
Tobias, Peter S.
Pugin, jerome
Application Number:
JP51038296A
Publication Date:
March 14, 2007
Filing Date:
September 15, 1995
Export Citation:
Assignee:
THE SCRIPPS RESEARCH INSTITUTE
International Classes:
A61K39/395; C12N15/02; A61K45/00; A61P1/16; A61P7/02; A61P11/00; A61P13/02; A61P15/00; A61P31/04; C07K16/18; C07K16/24; C07K16/28; C12P21/08; A61K38/00; C12R1/91
Domestic Patent References:
| JP5501399A |
Other References:
Beekhuizen, H. et al., The Journal of Immunology, 1991年,vol.147, no.11, pp.3761-3767
Weingarten, R. et al., Chemical Abstract, 1993年,vol.119, p.723
Zhang, Y. et al., Journal of Clinical Investigation, 1993年,vol.91. no.5, pp.2076-2083
Weingarten, R. et al., Chemical Abstract, 1993年,vol.119, p.723
Zhang, Y. et al., Journal of Clinical Investigation, 1993年,vol.91. no.5, pp.2076-2083
Attorney, Agent or Firm:
Yusuke Hiraki
Ishii Teiji
Ishii Teiji