Title:
トロンビン阻害剤メラガトランを含む水性医薬製剤、および血栓塞栓症の処置において経鼻投与に使用するための医薬の製造における該製剤の使用。
Document Type and Number:
Japanese Patent JP2006507323
Kind Code:
A
Abstract:
An aqueous pharmaceutical formulation comprising the thrombin inhibitor HOOC-CH2-(R)-Cgl-Aze-Pab (melagatran), or a pharmaceutically-acceptable derivative thereof, a process for the preparation of such a pharmaceutical formulation, the use of such a formulation in the treatment of thromboembolism as well as a method of treating a patient in need of antithrombotic treatment and thromboembolism by using said formulation via nasal administration.
Inventors:
Edman, Peter
Wing Strand Karin
Wing Strand Karin
Application Number:
JP2004551332A
Publication Date:
March 02, 2006
Filing Date:
November 11, 2003
Export Citation:
Assignee:
AstraZeneca Activrag
International Classes:
A61K31/397; A61K9/00; A61K9/08; A61K38/55; A61P7/02; C07D205/04; A61K47/18; A61K47/20
Attorney, Agent or Firm:
Kazuo Shamoto
Tadashi Masui
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
Takumi Terachi
Tadashi Masui
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
Takumi Terachi