Title:
縮合した2,3―ベンゾジアゼピン誘導体及びAMPA―レセプター抑制剤としての使用
Document Type and Number:
Japanese Patent JP4141499
Kind Code:
B2
Abstract:
The invention concerns compounds of formula (I), in which R1, R2, R3 and R4 mean hydrogen or different substituents; X means hydrogen or halogen; Y means C1-6 alkoxy or X and Y together mean -O-(CH2)n-O-; n means 1, 2 or 3; and A together with nitrogen forms a saturated or unsaturated five-member heterocycle which can contain between 1 and 3 nitrogen atoms and/or an oxygen atom and/or one or two carbonyl groups. Owing to their non-competitive inhibiting of the AMPA receptors, these compounds can be used as medicaments for treating diseases of the central nervous system.
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Inventors:
Herneje Chusdy
Tamasi Harmoly
Gizela Abraham
Sandor Soliyeom
Istovan Taranava
Pearl bergeny
Ferenc Andrassy
Istovan ring
Antal Shimai
Melinda Girl
Katalin Holvert
Esther Saint Cutie
Martha Sir Erosi
Istvan Paradis
Tamasi Harmoly
Gizela Abraham
Sandor Soliyeom
Istovan Taranava
Pearl bergeny
Ferenc Andrassy
Istovan ring
Antal Shimai
Melinda Girl
Katalin Holvert
Esther Saint Cutie
Martha Sir Erosi
Istvan Paradis
Application Number:
JP52724897A
Publication Date:
August 27, 2008
Filing Date:
January 29, 1997
Export Citation:
Assignee:
Schering Aktiengesellschaft
International Classes:
C07D243/02; A61K31/00; C07D487/04; A61K31/55; A61K31/551; A61K31/675; A61P9/00; A61P9/10; A61P25/06; A61P25/08; A61P25/14; A61P25/16; A61P25/18; A61P25/22; A61P25/28; A61P25/30; A61P43/00; C07D491/04; C07D491/056; C07D491/14; C07D491/147; C07D498/04; C07D498/14; C07F9/6561
Foreign References:
| US5459137 | ||||
| WO1995001357A1 |
Attorney, Agent or Firm:
Toshio Yano
Toshiomi Yamazaki
Takuya Kuno
Reinhard Einsel
Toshiomi Yamazaki
Takuya Kuno
Reinhard Einsel