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Title:
アミロイド結合剤としてのバクテリオファージのP3の使用
Document Type and Number:
Japanese Patent JP6440765
Kind Code:
B2
Abstract:
The invention relates to agents and to pharmaceutical compositions for reducing the formation of amyloid and/or for promoting the disaggregation of amyloid proteins. The compositions may also be used to detect amyloid.

Inventors:
Rajaraman Krishnan
Application Number:
JP2017074284A
Publication Date:
December 19, 2018
Filing Date:
April 04, 2017
Export Citation:
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Assignee:
Pro Clara Biosciences, Inc.
International Classes:
C12N15/62; C12N1/15; C12N1/21; C12N5/10; C12P21/02
Domestic Patent References:
JP2008528688A
Foreign References:
WO2010060073A2
US20110182948
Other References:
KONG, Bo et al,Display of aggregation-prone ligand binding domain of human PPAR gamma on surface of bacteriophage l,Acta Pharmacologica Sinica,2006年,Vol.27, No.1,p.91-99
KATHER INSA,A Stable Disulfide-free Gene-3-protein of Phage fd Generated by In vitro Evolution,JOURNAL OF MOLECULAR BIOLOGY,英国,ACADEMIC PRESS,2005年12月 2日,V354 N3,P666-678
Attorney, Agent or Firm:
Hidesaku Yamamoto
Natsuki Morishita
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto