Title:
脳腫瘍の処置及び可視化における生体分子標的の使用法
Document Type and Number:
Japanese Patent JP2004537282
Kind Code:
A
Abstract:
The present invention relates to the use of proteins that are differentially expressed in primary brain tumor tissues, as compared to normal brain tissues, as biomolecular targets for brain tumor treatment therapies. Specifically, the present invention relates to the use of immunotherapeutic and immunoimaging agents which specifically bind to one or more of the identified brain tumor protein targets. The present invention also provides compounds and pharmaceutically acceptable compositions for administration in the methods of the invention. The present invention also provides novel splice variants of protein PTP , PTP SM1 and PTP SM2. Nucleic acid probes specific for the spliced mRNA encoding these variants and affinity reagents specific for the novel proteins are also provided.
Inventors:
Mueller Sabin
Melcher Thorsten
Chin Daniel Jay.
Melcher Thorsten
Chin Daniel Jay.
Application Number:
JP2002575022A
Publication Date:
December 16, 2004
Filing Date:
March 22, 2002
Export Citation:
Assignee:
AG Therapeutics
International Classes:
C12N15/09; A61K45/00; A61K49/00; A61P35/00; C07K14/47; C12M1/00; C12M1/34; C12Q1/68; (IPC1-7): C12N15/09; A61K45/00; A61K49/00; A61P35/00; C07K14/47; C12M1/00; C12M1/34; C12Q1/68
Attorney, Agent or Firm:
Hatsushi Shimizu
Kazunori Hashimoto
Kazunori Hashimoto