Title:
USE OF COMPLEMENT PATHWAY INHIBITOR TO TREAT OCULAR DISEASE
Document Type and Number:
Japanese Patent JP2019043963
Kind Code:
A
Abstract:
To provide complement pathway inhibitors for treating ocular diseases.SOLUTION: The present invention relates to complement inhibitors for the treatment of ocular related conditions or diseases, such as age-related macular degeneration (AMD), diabetic retinopathy, ocular angiogenesis (such as ocular neovascularization affecting choroidal, corneal, or retinal tissue), and other ocular conditions involving complement activation. The treatment of AMD includes both the dry and wet forms of AMD. The complement inhibitors of the present invention include, but are not limited to, those inhibiting the alternative complement pathway, such as Factor D, properdin, Factor B, Factor Ba, and Factor Bb, and the classical complement pathway, such as C3a, C5, C5a, C5b, C6, C7, C8, C9 and C5b-9.SELECTED DRAWING: None
Inventors:
FUNG SEK CHUNG
YAO ZHENGBIN
YAO ZHENGBIN
Application Number:
JP2018238998A
Publication Date:
March 22, 2019
Filing Date:
December 21, 2018
Export Citation:
Assignee:
GENENTECH INC
International Classes:
A61K45/00; A61K9/06; A61K9/08; A61K9/70; A61K31/7105; A61K31/713; A61K38/02; A61K39/395; A61K48/00; A61P9/00; A61P9/10; A61P27/02; A61P27/04
Attorney, Agent or Firm:
Hidesaku Yamamoto
Natsuki Morishita
Natsuki Morishita