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Title:
Use of a compound containing peptide containing Grishin * arginine * Grishin * cysteic acid * threonine * proline in manufacture of medical supplies
Document Type and Number:
Japanese Patent JP5912202
Kind Code:
B2
Abstract:
Compounds comprising R-G-Cysteic Acid (i.e., R-G-NH-CH(CH2- SO3H)COOH or Arg-Gly-NH-CH(CH2-SO3H)COOH) and derivatives thereof, including pharmaceutically acceptable salts, hydrates, stereoisomers, multimers, cyclic forms, linear forms, drug-conjugates, pro-drugs and their derivatives. Also disclosed are methods for making and using such compounds including methods for inhibiting cellular adhesion to RGD binding sites or delivering other diagnostic or therapeutic agents to RGD binding sites in human or animal subjects.

Inventors:
McKell, Michael John
Park, John
Application Number:
JP2015117644A
Publication Date:
April 27, 2016
Filing Date:
June 10, 2015
Export Citation:
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Assignee:
ALLEGRO PHARMACEUTICALS,INC.
International Classes:
A61K38/00; A61P17/02; A61P27/02; A61P35/00; A61P35/04
Other References:
Peter L, et al.,Antiplatelet and antithrombotic agents: From viper venom proteins, to peptides and peptidomimetics, to small organic molecules,Advances in Medicinal Chemistry,1995年,Vol.3,p.57-111
Attorney, Agent or Firm:
Makoto Onda
Hironobu Onda
Atsushi Honda