Title:
ハロフラボノイド及び/又はニトロ置換フラボノイドの抗不安薬としての使用
Document Type and Number:
Japanese Patent JP4584362
Kind Code:
B2
Abstract:
Methods of treating anxiety with flavonoid compounds according to Formula (I) and dimers thereof, compounds of Formula (I) and dimers thereof, use of compounds of Formula (I) and pharmaceutical formulations comprising flavonoids of Formula (I) and dimers thereof.
Inventors:
Paladini Alejandro Constantino
Medina Jorge Oratio
Medina Jorge Oratio
Application Number:
JP54247998A
Publication Date:
November 17, 2010
Filing Date:
March 25, 1998
Export Citation:
Assignee:
University of Strathclyde
International Classes:
C07D311/30; A61K31/352; A61P25/22
Domestic Patent References:
| JP4502761A | ||||
| JP61243019A | ||||
| JP60028971A | ||||
| JP59222486A | ||||
| JP59176272A | ||||
| JP9501440A |
Foreign References:
| WO1997014414A1 |
Other References:
ANKHIWALA, M.D., J. Inst. Chem., 67(4), pp.121-122 (1995)
ANKHIWALA, M.D., J. Inst. Chem., 67(2), pp.58-59 (1995)
ANKHIWALA, M.D., J. Inst. Chem., 65(5), pp.155-157 (1993)
ANKHIWALA, M.D., et al., J. Inst. Chem., 62(6), pp.223-224 (1990)
ANKHIWALA, M.D., J. Indian Chem. Soc., 67(11), pp.913-915 (1990)
ANKHIWALA, M.D., et al., J. Indian Chem. Soc., 66(7), pp.482-484 (1989)
ARES, J.J., et al., J. Org. Chem., 58, pp.7903-7905 (1993)
ADAM, W., et al., J. Org. Chem., 56, pp.7292-7297 (1991)
DONNELLY, J.A., et al., Tetrahedron, 46(20), pp.7219-7226 (1990)
ADAM, W., et al., Tetrahedron Lett., 32(8), pp.1041-1044 (1991)
LU, Y.-F., et al., Biochem. Pharmacol., 51, pp.1077-1087 (1996)
KROL, W. et al., Arzneim.-Forsch./Drug Res., 45(II)(7), pp.815-818 (1995)
YAMAMOTO, K., et al., J. Pharmacobio-Dyn., 15, pp.59-66 (1992)
CUNNINGHAN, B.D.M., et al,., Anti-Cancer Drug Design, 7, pp.365-384 (1992)
HOSHINO, Y., et al., Bull. Chem. Soc. Jpn., 60(5), pp.1919-1920 (1987)
星野 行男ら, 日本化学会誌, (9), pp.1564-1567 (1982)
VIOLA, H., et al., Bioorg. Med. Chem. Lett., 7(3), pp.373-378 (1997)
MARDER, M., et al., Bioorg. Med. Chem. Lett., 5(22), pp.2717-2720 (1995)
WALFMAN, C., et al., Eur. J. Pharmacol., 318, pp.23-30 (1996)
MARDER, M., et al., Biochem. Biophys. Res. Commun., 223, pp.384-389 (1996)
OKUYAMA, E., et al., Chem. Pharm. Bull., 44(2), pp.333-336 (1996)
NIELSEN, M., et al., Biochem. Pharmacol., 37(17), pp.3285-3287 (1988)
ANKLHAWADA, M.D., J. Inst. Chem., 68(7), pp.409-410 (1991)
WURM, G., et al., Arch. Pharmaz., 308(9), pp.723-725 (1975)
ANKHIWALA, M.D., J. Inst. Chem., 67(2), pp.58-59 (1995)
ANKHIWALA, M.D., J. Inst. Chem., 65(5), pp.155-157 (1993)
ANKHIWALA, M.D., et al., J. Inst. Chem., 62(6), pp.223-224 (1990)
ANKHIWALA, M.D., J. Indian Chem. Soc., 67(11), pp.913-915 (1990)
ANKHIWALA, M.D., et al., J. Indian Chem. Soc., 66(7), pp.482-484 (1989)
ARES, J.J., et al., J. Org. Chem., 58, pp.7903-7905 (1993)
ADAM, W., et al., J. Org. Chem., 56, pp.7292-7297 (1991)
DONNELLY, J.A., et al., Tetrahedron, 46(20), pp.7219-7226 (1990)
ADAM, W., et al., Tetrahedron Lett., 32(8), pp.1041-1044 (1991)
LU, Y.-F., et al., Biochem. Pharmacol., 51, pp.1077-1087 (1996)
KROL, W. et al., Arzneim.-Forsch./Drug Res., 45(II)(7), pp.815-818 (1995)
YAMAMOTO, K., et al., J. Pharmacobio-Dyn., 15, pp.59-66 (1992)
CUNNINGHAN, B.D.M., et al,., Anti-Cancer Drug Design, 7, pp.365-384 (1992)
HOSHINO, Y., et al., Bull. Chem. Soc. Jpn., 60(5), pp.1919-1920 (1987)
星野 行男ら, 日本化学会誌, (9), pp.1564-1567 (1982)
VIOLA, H., et al., Bioorg. Med. Chem. Lett., 7(3), pp.373-378 (1997)
MARDER, M., et al., Bioorg. Med. Chem. Lett., 5(22), pp.2717-2720 (1995)
WALFMAN, C., et al., Eur. J. Pharmacol., 318, pp.23-30 (1996)
MARDER, M., et al., Biochem. Biophys. Res. Commun., 223, pp.384-389 (1996)
OKUYAMA, E., et al., Chem. Pharm. Bull., 44(2), pp.333-336 (1996)
NIELSEN, M., et al., Biochem. Pharmacol., 37(17), pp.3285-3287 (1988)
ANKLHAWADA, M.D., J. Inst. Chem., 68(7), pp.409-410 (1991)
WURM, G., et al., Arch. Pharmaz., 308(9), pp.723-725 (1975)
Attorney, Agent or Firm:
Masayuki Asakura