Title:
眼細胞生存の促進におけるラクリチンの使用
Document Type and Number:
Japanese Patent JP5122278
Kind Code:
B2
Abstract:
The present invention relates to the use of lacritin, and fragments, derivatives, and homologs thereof, and nucleic acid sequences encoding that protein. The invention relates to the use of lacritin as a growth factor human corneal epithelial cells and other select epithelial cells. The invention also relates to the use of lacritin in promoting ocular cell survival in response to an insult or injury, in protecting against ocular inflammation, and in promoting ocular wound repair.
Inventors:
Gordon W. Raleigh
Juff One
Juff One
Application Number:
JP2007513246A
Publication Date:
January 16, 2013
Filing Date:
May 06, 2005
Export Citation:
Assignee:
University of Virginia Patent Foundation
International Classes:
A61K38/00; A61K31/7088; A61K48/00; A61P17/00; A61P27/02; A61P29/00; A61P31/00; A61P37/00; A61P43/00; C12N5/071; C12N5/079; H02P1/00; C07K14/475; C12N15/09
Foreign References:
| WO2002065943A1 |
Other References:
WANG,J. et al,Lacrimal/salivary prosecretory mitogen 'lacritin' as a glandular stem cell survival factor,IOVS,2004年 4月24日,Vol.45, No.Suppl2,p.U328,Meeting Info.: Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology. Ft Lauderdale, FL, USA. April 24 -29, 2004. Assoc Res Vis & Ophthalmol. STN on the web(BIOSISファイル、表示形式はbib abs hitind)、ABフィールド、[online]、2004、[平成23年1月27日検索]、Accession No. 2005:457214
Attorney, Agent or Firm:
Mitsuo Tanaka
Hiroshi Yamazaki
Michiko Matsutani
Mina Shiga
Sakurai Yoko
Hiroshi Yamazaki
Michiko Matsutani
Mina Shiga
Sakurai Yoko
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