Title:
クエン酸に対し安定化された中性メタロプロテアーゼの使用と生産
Document Type and Number:
Japanese Patent JP5498951
Kind Code:
B2
Abstract:
The present invention provides methods and compositions comprising at least one neutral metalloprotease enzyme that has improved stability in the presence of a metal chelator. In some embodiments, the neutral metalloprotease finds use in cleaning and other applications comprising citrate. In some particularly preferred embodiments, the present invention provides methods and compositions comprising variant neutral metalloprotease(s) engineered to resist citrate-induced autolysis.
Inventors:
Homer, Ronaldas W Jay
Riu, Amy
Show, Andrew
Wallace, Louise
Riu, Amy
Show, Andrew
Wallace, Louise
Application Number:
JP2010532153A
Publication Date:
May 21, 2014
Filing Date:
October 23, 2008
Export Citation:
Assignee:
Danisco US Inc.
International Classes:
C12N15/09; C11D1/29; C11D3/386; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N9/54; D06L4/40
Domestic Patent References:
JP63264699A | ||||
JP62171681A |
Foreign References:
WO2007044993A1 |
Attorney, Agent or Firm:
Yuzo Yamazaki
Naoto Sugiyama
Shirogane Expo
Toshiaki Akamatsu
Okuko Masako
Ono Wataru
Tadao Naito
Katsuaki Tsunemitsu
Asako Ando
Hirofumi Higashino
Takeko Miko
Naoto Sugiyama
Shirogane Expo
Toshiaki Akamatsu
Okuko Masako
Ono Wataru
Tadao Naito
Katsuaki Tsunemitsu
Asako Ando
Hirofumi Higashino
Takeko Miko