紅潮および/または薬物誘発性体重増加を処置するためのサーチュイン活性化化合物の使用

Japanese Patent JP2008528510

A

Provided herein are methods and compositions for treating and/or preventing flushing and/or weight gain. Methods may comprise modulating the activity or level of a sirtuin, such as SIRT1 or Sir2. Exemplary embodiments include methods and compositions for counteracting drug-induced weight gain and/or drug-induced flushing by administering a sirtuin-activating compound.

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Sinclair, David
Milbern, michael
Langer, Robert S.
Westfal, Christoph H.

JP2007552335A

July 31, 2008

January 20, 2006

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Sir Tris Pharmaceuticals, Inc.

A61K45/00; A61K31/05; A61K31/135; A61K31/165; A61K31/166; A61K31/167; A61K31/175; A61K31/28; A61K31/343; A61K31/352; A61K31/36; A61K31/381; A61K31/415; A61K31/4162; A61K31/42; A61K31/422; A61K31/426; A61K31/428; A61K31/4375; A61K31/44; A61K31/451; A61K31/4525; A61K31/455; A61K31/4709; A61K31/473; A61K31/4743; A61K31/498; A61K31/517; A61K31/519; A61K31/5375; A61K31/5383; A61K31/549; A61K31/55; A61K31/56; A61K31/57; A61K31/64; A61K31/65; A61K31/665; A61K31/7034; A61K31/7048; A61K38/28; A61P3/04; A61P3/10; A61P9/12; A61P15/12; A61P15/18; A61P25/24; A61P43/00; C07K7/06

Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita

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