Title:
【発明の名称】T細胞リンフォカインの産生を誘発する組成物でのステロイドホルモンの使用
Document Type and Number:
Japanese Patent JP2505313
Kind Code:
B2
Abstract:
Disclosed is a method for enhancing the production of T cell lymphokines, which comprises exposing T cell lymphocytes which have a potential to make selected T cell lymphokines to an appropriate concentration of at least one particular steroid hormone prior to cellular activation. Also disclosed are applications of the method for clinically diagnosing abnormal interleukin production, maintaining in vitro tissue cultures of T cells, overcoming certain types of immunosuppression caused by elevated GCS levels, caused by endogenous production or exogenous administration, use as a vaccine adjuvant to selectively direct the vaccine-induced immune response down a protective, rather than a potentially pathologic or non-protective, immunologic pathway, as a treatment for naturally occuring aging-related decreases in immune function, as a treatment for stress or trauma-induced decreases in immune function, and as an agent to facilitate desensitization to agents to which a warm-blooded animal is allergic.
Inventors:
DEINZU REIMONDO EI
ARANEO BAABARA EI
ARANEO BAABARA EI
Application Number:
JP51381890A
Publication Date:
June 05, 1996
Filing Date:
September 25, 1990
Export Citation:
Assignee:
UNIV UTAH
International Classes:
A61K31/565; A61K31/57; A61K31/59; A61K39/02; A61K39/12; A61K39/395; A61K45/06; A61P37/00; C07J5/00; G01N33/68; (IPC1-7): A61K31/57; A61K39/395; C07J5/00
Attorney, Agent or Firm:
Shusaku Yamamoto