Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
レイン複合物、その調整方法及び糖尿病ネフローゼ薬物、腸癒着薬物、骨関節炎薬物への利用
Document Type and Number:
Japanese Patent JP5106392
Kind Code:
B2
Abstract:
The conjugates of present invention are formed by the combination of rhein or their analogues with the organic bases or amino acids in molecular force between them. The methods for preparing the conjugates and their uses for manufacturing medicines in the treatment of diabetic nephrosis, recovery of gastrointestinal function and prevention of intestinal adhesion, as well as treatment of osteoarthritis, rheumatic arthritis and rheumatoid arthritis are also described. Rhein or their analogues as the left part of general formula (I) is selected from (1) the compounds of rhein or their analogues, in which one or two substituents of R2~R3 and R6~R7 are COOH at least two substituents of R1~8 are -H; or (2) the rhein-containing extract derived from plants. In general formula (I), M represents nitrogen-containing organic bases or basic amino acids.

Inventors:
CONG,Xiaodong
Application Number:
JP2008520693A
Publication Date:
December 26, 2012
Filing Date:
July 10, 2006
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
CONG,Xiaodong
International Classes:
C07C50/34; A61K9/06; A61K9/10; A61K9/107; A61K9/12; A61K9/20; A61K9/48; A61K9/70; A61K31/192; A61K31/194; A61K36/48; A61K36/70; A61K47/18; A61K47/22; A61K47/26; A61P1/04; A61P3/10; A61P19/02
Domestic Patent References:
JP48034865A
Foreign References:
US6197818
Other References:
International Journal of Clinical and Experimental Pathology,1993年,47,pp.110-119
Journal of Biosciences,2002年,57C,pp.822-827
薬物分析雑誌,2003年,23(4),pp.279-283
Attorney, Agent or Firm:
Miaki Kametani
Tetsuo Kanamoto
Koji Hagiwara



 
Previous Patent: 創傷包帯材料

Next Patent: SHIELD MACHINE