Title:
NS4核酸及びポリペプチド並びに体重異常の治療のための使用
Document Type and Number:
Japanese Patent JP2005500030
Kind Code:
A
Abstract:
The present invention is directed to novel polypeptides NS4 and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention. Furthermore, methods of treating body weight disorders (e.g., obesity, cachexia or anorexia) are provided.
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Inventors:
Goddard, Audrey
Bread james
Wood, William Eye.
Bread james
Wood, William Eye.
Application Number:
JP2003503819A
Publication Date:
January 06, 2005
Filing Date:
April 03, 2002
Export Citation:
Assignee:
GENENTECH,INC.
International Classes:
A61K38/00; A61K38/17; A61K39/00; A61K39/395; A61P1/14; A61P3/00; A61P3/04; A61P3/06; A61P7/00; C07H21/04; C07K14/00; C07K14/435; C07K14/47; C07K14/705; C07K16/18; C07K16/46; C07K19/00; C12N1/19; A01K67/027; C12N1/21; C12N5/00; C12N5/06; C12N5/10; C12N9/00; C12N15/00; C12N15/09; C12N15/12; C12N15/62; C12N15/63; C12P21/02; C12P21/08; C12Q1/02; G01N33/15; G01N33/50; G01N33/53; G01N33/566; G01N33/68; C12N; C12Q; (IPC1-7): C12N15/09; A01K67/027; A61K38/00; A61P1/14; A61P3/00; A61P3/04; A61P3/06; A61P7/00; C07K14/47; C07K16/18; C07K19/00; C12N1/19; C12N1/21; C12N5/10; C12P21/02; C12Q1/02; G01N33/15; G01N33/50
Attorney, Agent or Firm:
Sonoda Yoshitaka
Kobayashi Yoshinori
Kobayashi Yoshinori