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Title:
有意な流出阻害を示さない、親油性薬物を可溶化するビタミンETPGS分子を含む医薬製剤及びこのような医薬製剤の使用
Document Type and Number:
Japanese Patent JP2008514714
Kind Code:
A
Abstract:
Compounds and compositions are disclosed for increasing the bioavailability of lipophilic drugs, and more specifically, to solubilizing lipophilic drugs using bioenhancers that cause no efflux inhibition or a desired degree of efflux inhibition. Methods of making and using such compositions are also disclosed.

Inventors:
Hyatt, John Anthony
Zima, George Chester
Edgar, Kevin Joseph
Navarro, Lisa Toner
Lehr, Klaus-Michael
Coronot, Efa-Maria
Singleton, Andy Hugh
Valdes, Christiane
Schurfer, Urich Friedrich
Wempe, Michael Fitzpatrick
Application Number:
JP2007534708A
Publication Date:
May 08, 2008
Filing Date:
September 29, 2005
Export Citation:
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Assignee:
EASTMAN CHEMICAL COMPANY
International Classes:
A61K47/48; A61K9/127; A61K31/355; A61K31/385; A61P3/02
Attorney, Agent or Firm:
Atsushi Aoki
Takashi Ishida
Tetsuji Koga