Title:
UTILIZATION OF PHAGOCYTE CELL LINE
Document Type and Number:
Japanese Patent JPS60256377
Kind Code:
A
Abstract:
The property of phagocyte cells to show chemiluminescence when activated by certain chemical or immunological agents is used for a qualitative and quantitative analysis of such agents in biological fluids. A variety of factors such as opsonizing anti-bodies, complement, inhibitors, membrane-specific anti-bodies, and their antigens, membrane-specific lectins, lymphokines, endotoxins, toxic substances and others can be analyzed in this way. The new method finds application in the biotechnical, clinical, immunological and pharmacological fields, with a special preference for toxicological screening of pharmaceuticals. The phagocyte cells needed for the analysis can be derived from a continuous phagocyte cell line and a method of producing such a cell line is provided.
Inventors:
PATORITSUKU DOU BETOSERIEERU
Application Number:
JP8210685A
Publication Date:
December 18, 1985
Filing Date:
April 16, 1985
Export Citation:
Assignee:
INOFUI NV SA
International Classes:
A61K35/12; A61K35/28; A61K38/16; C12N5/00; C12N5/02; C12N5/10; C12N5/16; C12N15/02; C12P21/08; G01N33/52; C12Q1/02; G01N33/50; G01N33/577; C12R1/91; (IPC1-7): A61K35/12; A61K35/28; A61K37/04; C12N5/00; C12N15/00; C12Q1/02; C12R1/91; G01N33/52; G01N33/577
Domestic Patent References:
| JPS5417185A | 1979-02-08 |
Attorney, Agent or Firm:
Aoyama