To obtain Sendai virus vector capable of simply and safely producing a vaccine against strong poison type influenza which has been difficult hitherto by retaining influenza virus protein or its part so as to be expressible.
The Sendai virus vector retains strong poison type influenza virus protein such as subtype H5 or subtype H7 or its part so as to be expressible. Furthermore, the protein is preferably HA protein of A type influenza virus and the influenza vaccine is preferably produced by inoculating Sendai virus vector into hen's egg, proliferating Sendai virus complex in the hen's egg, recovering the proliferated Sendai virus vector from chorio-allantoic liquid of the hen's egg and inactivating the Sendal virus vector. A kit for ELISA of antibody is preferably prepared by using a protein for immunogen capable of obtaining by expressing a gene encoding a protein derived from pathogen integrated into Sendai virus vector so as to be expressible.
KIYOTANI KATSUHIRO
YOSHIDA TETSUYA
SHIODA TATSUO
TORIYOSHI HIDENOBU
TAKEBE YUTAKA
NAGAI YOSHIYUKI
