To provide a valve guard of a high-pressure gas cylinder allowing protection of a cylinder valve from a flying stone and determination of a direction and a fixed position of the high-pressure gas cylinder.

A whirl-stop bracket 7 engaged with the outer peripheral surface of the cylinder valve 2 passing through a hole 4 in a valve guard body 1 is fixed to the valve guard body 3 that has the hole 4 penetrating the cylinder valve 2 screwed with the end of the high-pressure gas cylinder 1, surrounds the cylinder valve 2 having the hole 4, and is mounted to a pedestal fixed to a frame of a vehicle.