To provide a vibration-isolating structure of an electric wheelchair improving the vibration-isolating performance by suppressing vibration transmitted from both of front/rear wheels.

A sitting part seat frame is mounted on a lower frame 4 provided with the front wheels 1, the rear wheels 2 and an automatic traveling driving motor. An upper frame 7 having both-side side frames 7a whose front/rear are connected by cross bars 3 respectively is inserted between the lower frame 4 and the seat frame 20, suspension springs 10 are interposed between four both-side front/rear parts of the upper frame and the lower frame 4, and a vibration-isolating rubber 30 exhibiting a buffer action relative to a high frequency component vibration compared with the suspension springs 10 is interposed between four both-side front/rear parts of the upper frame 7 and the seat frame 20.