Title:
細胞培養におけるウイルスの生産
Document Type and Number:
Japanese Patent JP7189017
Kind Code:
B2
Abstract:
The present invention relates to methods of replicating viruses in vitro. In particular, the invention relates to a genetically modified population of cells, and/or a population of cells treated with an exogenous compound, wherein the cells are capable of producing more virus than cells lacking the genetic modification and/or lacking treatment with the exogenous compound. The invention also relates to methods of producing populations of such cells, as well as the use of the viruses obtained to prepare vaccine compositions.
Inventors:
Andrew Bean
John William Lowenthal
Luis Fernando Marabellotega
Ralph A. Trip
John William Lowenthal
Luis Fernando Marabellotega
Ralph A. Trip
Application Number:
JP2018526926A
Publication Date:
December 13, 2022
Filing Date:
November 23, 2016
Export Citation:
Assignee:
Commonwealth Scientific and Industrial Research Organization
University of Georgia Research Foundation Incorporated
University of Georgia Research Foundation Incorporated
International Classes:
C12N7/00; C12N5/10; C12N15/113
Domestic Patent References:
| JP2002517230A |
Foreign References:
| WO2014078502A1 | ||||
| CN104694576A | ||||
| CN104560864A |
Other References:
Pritam Das,Journal of Neuroinflammation,2006年,3(17),1-13
Asiel A. Benitez,Cell Reports,2015年06月23日,Vol. 11, No. 11,pp.1714-1726
Herbert Tilg,The journal of Immunology,150(10),4687-4692
Benitez, Asiel A.; Panis, Maryline; Varble, Andrew; Shim, Jaehee V.; tenOever, Benjamin R.,In Vivo RNAi Screening Identifies MDA5 as a Significant Contributor to the Cellular Defense against Influenza A Virus,Cell Reports,2015年06月23日,Vol. 11, No. 11,pp.1714-1726
Herbert Tilg,Induction of circulating IL-1 receptor antagonist by IFN treatment,The journal of Immunology,150(10),4687-4692
Benitez, Asiel A.; Panis, Maryline; Varble, Andrew; Shim, Jaehee V.; tenOever, Benjamin R.,In Vivo RNAi Screening Identifies MDA5 as a Significant Contributor to the Cellular Defense against Influenza A Virus,Cell Reports,2015年06月23日,Vol. 11, No. 11,,pp.1714-1726
Asiel A. Benitez,Cell Reports,2015年06月23日,Vol. 11, No. 11,pp.1714-1726
Herbert Tilg,The journal of Immunology,150(10),4687-4692
Benitez, Asiel A.; Panis, Maryline; Varble, Andrew; Shim, Jaehee V.; tenOever, Benjamin R.,In Vivo RNAi Screening Identifies MDA5 as a Significant Contributor to the Cellular Defense against Influenza A Virus,Cell Reports,2015年06月23日,Vol. 11, No. 11,pp.1714-1726
Herbert Tilg,Induction of circulating IL-1 receptor antagonist by IFN treatment,The journal of Immunology,150(10),4687-4692
Benitez, Asiel A.; Panis, Maryline; Varble, Andrew; Shim, Jaehee V.; tenOever, Benjamin R.,In Vivo RNAi Screening Identifies MDA5 as a Significant Contributor to the Cellular Defense against Influenza A Virus,Cell Reports,2015年06月23日,Vol. 11, No. 11,,pp.1714-1726
Attorney, Agent or Firm:
Aoki Atsushi
Shinji Mihashi
Youichi Watanabe
Nakajima Masaru
Ryotaro Takei
Hidenao Tsuda
Shinji Mihashi
Youichi Watanabe
Nakajima Masaru
Ryotaro Takei
Hidenao Tsuda
Previous Patent: Polyurethane binder containing alcohol solvent
Next Patent: Vibration reduction system and method for power tools
Next Patent: Vibration reduction system and method for power tools