Title:
ビタミンD誘導体
Document Type and Number:
Japanese Patent JP3706104
Kind Code:
B2
Abstract:
The object of the present invention is to provide vitamin D derivatives that have excellent physiological activities as medicines, particularly as therapeutic agents for skin diseases such as psoriasis, and that have a reduced hypercalcemic effect. The present invention provides a vitamin D derivative of Formula (1): wherein X represents an oxygen atom or a sulfur atom; m represents a number of 1 to 3; R1 and R2 each represent a hydrogen atom or an alkyl group; R4 and R5 each represent a hydrogen atom or a hydroxyl group, etc.; R3 represents -YR8, etc.; R6 represents a hydrogen atom, etc.; and R7 represents a hydrogen atom, etc.
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Inventors:
Kazumi Morikawa
Masayuki Omori
Kazuki Shimizu
Akira Kawase
Takeshi Emura
Masayuki Omori
Kazuki Shimizu
Akira Kawase
Takeshi Emura
Application Number:
JP2002510437A
Publication Date:
October 12, 2005
Filing Date:
June 14, 2001
Export Citation:
Assignee:
Chugai Pharmaceutical Co., Ltd.
International Classes:
C07J5/00; A61K31/592; A61K31/593; A61P3/02; A61P17/00; C07B61/00; C07C235/06; C07C401/00; C07D295/185; C07F7/18; C07J1/00; C07J7/00; C07J9/00; (IPC1-7): C07C401/00; A61K31/59; A61P3/02; A61P17/00; A61P17/06
Domestic Patent References:
| JP8509971A | ||||
| JP10231284A | ||||
| JP7330714A | ||||
| JP7179418A | ||||
| JP8113559A |
Attorney, Agent or Firm:
Kazuo Shamoto
Tadashi Masui
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
Keiko Kanemoto
Tadashi Masui
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
Keiko Kanemoto