Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
VITAMIN D2 DERIVATIVE
Document Type and Number:
Japanese Patent JPH05155848
Kind Code:
A
Abstract:

PURPOSE: To provide a novel low-toxic compound having powerful vitamin D3-like activity, useful as a therapeutic agent for calcium dysbolism and osteoporosis.

CONSTITUTION: A compound of formula I (R is methyl or ethyl), e.g. (24R)-1α,25- dihydroxy-26,27-dimethylvitamin D2. The compound of the formula I can be obtained by the following processes: the protecting group of a compound of formula III produced from a compound of formula II as starting material is eliminated to form a compound of formula IV, which is, in turn, irradiated with light of rays using a medium-pressure mercury lamp and then thermally isomerized.


Inventors:
Kikuchi, Yoshiyuki
Kotomo, Susumu
Higuchi, Shohei
Harada, Masahiro
Ikegawa, Nobuo
Application Number:
JP1991000326111
Publication Date:
June 22, 1993
Filing Date:
December 10, 1991
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
CENTRAL GLASS CO LTD
TAISHO PHARMACEUT CO LTD
International Classes:
A61K31/59; A61P3/00; A61P3/02; A61P43/00; C07C401/00; (IPC1-7): A61K31/59; C07C401/00



 
Previous Patent: JPS5155847

Next Patent: JP5155849