To provide a pharmacological composition containing a water-soluble extract originated from a plant as an effective component for suppressing the proliferation of a tumor cell or cancer cell, specially liver cancer cell, lung cancer cell, and breast cancer cell.
The water-soluble extract originated from a plant of the genus Solanum substantially consists of at least 60-90% of solamargine and solasonine. The method of preparing the water-soluble extract originated from a plant belonging to the genus Solanum includes a process for hydrolysis using an acid, a process for precipitation using a base, and a process for separation using chloroform, an alcohol and water as an extraction solvent. The water-soluble extract can be used as an effective component in the pharmacological composition for inhibiting the proliferation of the tumor cell or cancer cell, specially liver cancer cell, lung cancer cell and breast cancer cell.
| JP2014516078 | New Taccaronolid Microtubule Stabilizer |
KUO KOU WHA
| JP3940928B2 | 2007-07-04 |
| WO2003029269A1 | 2003-04-10 | |||
| WO2000061153A1 | 2000-10-19 |
Kakehi Yuro
Kenji Saito
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