To provide a wheel-driven bag and a wheel-driven antitheft system with an improved antitheft property.

When a person possessing a key 5 inserts the key 5 in a key insertion hole 6, a brake gear 13 moves upward, and a tooth part 14 provided in the lower end of the brake gear 13 is separated from a motor gear 11, so that wheels 4 are rotated by a rotating force of the motor 9 to easily carry the wheel-driven bag 1 with an assisting force. On the other hand, when the key 5 is not inserted in the key insertion hole 6, the brake gear 13 moves downward and the tooth part 14 is threadedly engaged with the motor gear 11, so that the motor 9 becomes non-rotatable to prevent the rotation of the wheel 4. Thereby if a person possessing no key pulls the wheel-driven bag 1 for a stealing purpose with the key non-inserted, the wheel 4 never rotates to prevent the theft of the wheel-driven bag 1.