Title:
全細胞の生体触媒
Document Type and Number:
Japanese Patent JP2013510587
Kind Code:
A
Abstract:
The present invention relates to a method for producing a product of a reaction catalysed by a nitrilase, which method comprises the steps (i) providing a microorganism comprising said nitrilase located on its surface, and/or a membrane preparation of said microorganism, and (ii) contacting the microorganism and/or the membrane preparation thereof with one or more nitrilase substrates under conditions compatible with nitrilase activity. The present invention further relates to a method for producing enantiomerically pure (R)-mandelic acid using the nitrilase-displaying whole cell biocatalyst or membrane preparation thereof for the conversion of racemic mandelonitrile.
Inventors:
Jose, Joachim
Mars, Ruth
Detzel, Christian
Mars, Ruth
Detzel, Christian
Application Number:
JP2012539221A
Publication Date:
March 28, 2013
Filing Date:
November 16, 2010
Export Citation:
Assignee:
ZYRUS Beteiligungsgesellschaft mbH & Co. Patente I KG
International Classes:
C12P7/42; C12N1/21; C12N9/78; C12N15/09
Other References:
JPN6014054117; Ａｐｐｌ．Ｍｉｃｒｏｂｉｏｌ．Ｂｉｏｔｅｃｈｎｏｌ．，２００６，６９（６），ｐ．６０７-１４
JPN5013000621; Ｂｉｏｐｒｏｃｅｓｓ Ｂｉｏｓｙｓｔ．Ｅｎｇ．，２００５，２７（６），ｐ．４１５-２４
JPN5013000621; Ｂｉｏｐｒｏｃｅｓｓ Ｂｉｏｓｙｓｔ．Ｅｎｇ．，２００５，２７（６），ｐ．４１５-２４
Attorney, Agent or Firm:
Kurata Masatoshi
Makoto Nakamura
Yoshihiro Fukuhara
Takashi Mine
Toshio Shirane
Nobuhisa Nogawa
Katsu Sunagawa
Makoto Nakamura
Yoshihiro Fukuhara
Takashi Mine
Toshio Shirane
Nobuhisa Nogawa
Katsu Sunagawa
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