Title:
Ｗｎｔシグナル阻害剤
Document Type and Number:
Japanese Patent JP6522502
Kind Code:
B2
Abstract:
A Wnt signaling inhibitor which comprises, as an active ingredient, a fused-ring heterocyclic compound represented by the following formula (IA) or a pharmaceutically acceptable salt thereof, and the like are provided:
(wherein, n 1A represents 0 or 1; n 2A and n 3A may be the same or different, and each represents 1 or 2; R 0A represents optionally substituted aryl or the like; R 2A represents a hydrogen atom or the like; R 3A represents an optionally substituted aromatic heterocyclic group or the like; X 1A , X 2A , X 3A and X 4A each represent CH or the like; Y 1A represents CH 2 or the like; Y 2A represents N or the like; and L A represents CH 2 or the like) .
Inventors:
Hiroshi Ishida
Keiichi Motozawa
Yusuke Miura
Ryuichiro Nakai
Ryoko Okada
Yuichi Takahashi
Keiichi Motozawa
Yusuke Miura
Ryuichiro Nakai
Ryoko Okada
Yuichi Takahashi
Application Number:
JP2015529571A
Publication Date:
May 29, 2019
Filing Date:
July 29, 2014
Export Citation:
Assignee:
Kyowa Hakko Kirin Co., Ltd.
International Classes:
A61K31/517; A61K31/519; A61K31/52; A61K31/53; A61K31/5377; A61K31/5383; A61P11/00; A61P19/02; A61P35/00; A61P43/00; C07D401/14; C07D405/14; C07D471/04; C07D487/04; C07D491/052; C07D491/056; C07D498/04; C07D519/00
Foreign References:
| CA2245896A1 |