To obtain a safe wrinkle preventive, capable of maintaining a fair complexion sustainably by compounding a highly useful, specific medicine(s) showing various excellent effects, e.g. making a complexion fair and antiinflammatroy effect, so as to prevent fine wrinkles caused by changed dryness of the horny cell layer.

This wrinkle preventive contains kojic acid and/or its derivative as the active ingredient(s). The kojic acid useful for the present invention is pure kojic acid (5-oxy-2-oxymethyl-γ-pyrone), a fermentation solution comprising kojic acid as the major ingredient, obtained by culturing known strains capable of producing kojic acid, the concentrate of the above fermentation solution, or the kojic acid extracted from the above fermentation solution and crystallized. Content of the active ingredient is 0.001 to 10wt.% based on the whole preventive.