Title:
ジルコニウム触媒によるβ-ジカルボニルのヒドロキシル化
Document Type and Number:
Japanese Patent JP4359500
Kind Code:
B2
Abstract:
The present invention pertains to a process for preparing a compound of Formula I that is achiral, racemic or enantiomerically enriched at the hydroxylation center indicated by * comprising contacting a compound of Formula II with an oxidant selected from oxygen, hydrogen peroxide, peracids or alkyl hydroperoxides in the presence of a zirconium complex, wherein R1, R2 and R3 are as defined in the disclosure. This invention also pertains to zirconium complexes useful in this procedure comprising zirconium and a ligand of Formula III or its enantiomer wherein J, R6 and n are as defined in the disclosure. This invention further pertains to a compound of Formula III or its enantiomer.
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Inventors:
Albert Loren, Casalnuovo
Application Number:
JP2003508481A
Publication Date:
November 04, 2009
Filing Date:
June 06, 2002
Export Citation:
Assignee:
E.I.DU PONT DE NEMOURS AND COMPANY
International Classes:
C07C67/31; C07D317/28; B01J31/22; C07B53/00; C07B61/00; C07C45/64; C07C49/185; C07C49/413; C07C49/523; C07C49/747; C07C49/757; C07C49/80; C07C69/738; C07C215/50; C07D209/12; C07D241/12; C07D273/04; C07D307/33; C07D307/34; C07D307/60; C07D307/83; C07D309/30; C07D309/32; C07D311/20; C07D311/56; C07D311/86; C07D313/04; C07D313/08; C07D317/32; C07D405/06; C07D405/12; C07F7/00; B01J21/06
Domestic Patent References:
| JP9512533A | ||||
| JP10017506A | ||||
| JP6504777A |
Other References:
TSHUVA, E. Y. et al.,Single-step synthesis of salans and substituted salans by Mannich condensation,Tetrahedron Letters ,2001年,42(36),p.6405-6407
BALSELLS, J. et al.,Achiral Tetrahydrosalen Ligands for the Synthesis of C2-Symmetric Titanium Complexes: A Structure and Diastereoselectivity Study,Inorganic Chemistry ,2001年,40(22),p.5568-5574
BOTTCHER, A. et al.,Syntheses, structures and magnetic properties of fluoro-bridged di- and tetranuclear chromium(III) complexes with tetrahydrosalen and substituted tetrahydrosalen derivatives as ligands. Crystal structure of an ethoxo-fluoro-bridged dichromium(III) complex and a tetrafluoro-bridged tetrachromium(III) complex,Acta Chemica Scandinavica ,1994年,48(12),p.967-980
BOTTCHER, A. et al.,Synthesis, structure and magnetic properties of mono- and dinuclear chromium(III) complexes with tetrahydrosalen and substituted tetrahydrosalen derivatives as ligands. Crystal structure of a phenoxo-bridged dichromium(III) complex,Acta Chemica Scandinavica ,1994年,48(12),p.981-988
KANATOMI, H.,The dehydrogenation of nickel(II) chelates of rac- and meso-2,2'-[(1,2-diphenylethylene)bis(iminomethylene)]diphenol and related compounds,Bulletin of the Chemical Society of Japan ,1983年,56(1),p.99-104
ELIAS, H. et al.,A dioxomolybdenum(VI) complex with a new enantiomerically pure tetrahydrosalen ligand,Acta Crystallographica, Section C: Crystal Structure Communications,1997年,C53(7),p.862-864
BALSELLS, J. et al.,Achiral Tetrahydrosalen Ligands for the Synthesis of C2-Symmetric Titanium Complexes: A Structure and Diastereoselectivity Study,Inorganic Chemistry ,2001年,40(22),p.5568-5574
BOTTCHER, A. et al.,Syntheses, structures and magnetic properties of fluoro-bridged di- and tetranuclear chromium(III) complexes with tetrahydrosalen and substituted tetrahydrosalen derivatives as ligands. Crystal structure of an ethoxo-fluoro-bridged dichromium(III) complex and a tetrafluoro-bridged tetrachromium(III) complex,Acta Chemica Scandinavica ,1994年,48(12),p.967-980
BOTTCHER, A. et al.,Synthesis, structure and magnetic properties of mono- and dinuclear chromium(III) complexes with tetrahydrosalen and substituted tetrahydrosalen derivatives as ligands. Crystal structure of a phenoxo-bridged dichromium(III) complex,Acta Chemica Scandinavica ,1994年,48(12),p.981-988
KANATOMI, H.,The dehydrogenation of nickel(II) chelates of rac- and meso-2,2'-[(1,2-diphenylethylene)bis(iminomethylene)]diphenol and related compounds,Bulletin of the Chemical Society of Japan ,1983年,56(1),p.99-104
ELIAS, H. et al.,A dioxomolybdenum(VI) complex with a new enantiomerically pure tetrahydrosalen ligand,Acta Crystallographica, Section C: Crystal Structure Communications,1997年,C53(7),p.862-864
Attorney, Agent or Firm:
Junji Yuda
Noriyuki Takebayashi
Chika Takagi
Noriyuki Takebayashi
Chika Takagi