Title:
両性イオン性タキキニン受容体拮抗薬
Document Type and Number:
Japanese Patent JP2004509160
Kind Code:
A
Abstract:
The present invention is directed to certain novel compounds represented by structural formula I:or a pharmaceutically acceptable salt thereof, wherein R3, R5, R6, R7, R8, R11, R12, R13, Q, W, X, Y and Z are defined herein. The invention is also concerned with pharmaceutical formulations comprising these novel compounds as active ingredients and the use of the novel compounds and their formulations in the treatment of certain disorders. The compounds of this invention are tachykinin receptor antagonists and are useful in the treatment of psychiatric disorders including depression and anxiety.
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Inventors:
Finke, Paul Yi
Moyler, Laura Sea
Mills, Thunder Gi
Matsukos, Malcolm
Qi, Hong Bo
Moyler, Laura Sea
Mills, Thunder Gi
Matsukos, Malcolm
Qi, Hong Bo
Application Number:
JP2002528644A
Publication Date:
March 25, 2004
Filing Date:
September 21, 2001
Export Citation:
Assignee:
MERCK & COMPANY INCOPORATED
International Classes:
A61K31/075; A61K31/135; A61K31/192; A61K31/216; A61K31/27; A61K31/40; A61K31/41; A61K31/445; A61K31/454; A61K31/5375; A61P1/04; A61P11/02; A61P11/06; A61P13/10; A61P25/00; A61P25/04; A61P25/26; A61P25/28; A61P27/02; A61P27/16; A61P29/00; C07C43/196; C07C51/09; C07C62/34; C07C69/708; C07C217/52; C07C229/22; C07C229/36; C07C229/46; C07C229/48; C07C271/24; C07C271/26; C07D205/04; C07D207/16; C07D211/60; C07D211/62; C07D257/04; C07D265/30; C07D401/04; (IPC1-7): C07C69/708; A61K31/075; A61K31/135; A61K31/192; A61K31/216; A61K31/27; A61K31/40; A61K31/41; A61K31/445; A61K31/454; A61K31/5375; A61P1/04; A61P11/02; A61P11/06; A61P13/10; A61P25/00; A61P25/04; A61P25/28; A61P27/02; A61P27/16; A61P29/00; C07C229/36; C07C271/24; C07C271/26; C07D207/16; C07D211/60; C07D211/62; C07D257/04; C07D265/30; C07D401/04
Attorney, Agent or Firm:
Yoshio Kawaguchi
Mitsuru Inoue
Akio Ichiiri
Makoto Ono
Katsuma Osaki
Mitsuru Inoue
Akio Ichiiri
Makoto Ono
Katsuma Osaki