Title:
MGLUR5アンタゴニスト活性を有するアセチレン誘導体
Document Type and Number:
Japanese Patent JP5036648
Kind Code:
B2
Abstract:
The invention provides compounds of formula I wherein n, A, R, R', R'', R0, X and Y are as defined in the description, and their preparation. The compounds of formula I are useful as pharmaceuticals.
Inventors:
Fabrizio Gasparini
Eve oberson
Gilfio Offner
Caspar Zimmermann
Terence W Heart
Eve oberson
Gilfio Offner
Caspar Zimmermann
Terence W Heart
Application Number:
JP2008179005A
Publication Date:
September 26, 2012
Filing Date:
July 09, 2008
Export Citation:
Assignee:
Novartis Age
International Classes:
A61K31/404; C07D215/26; A61K31/32; A61K31/4035; A61K31/405; A61K31/4439; A61K31/4709; A61K31/497; A61K31/5377; A61P25/00; A61P25/04; A61P25/08; A61P25/14; A61P25/16; A61P25/18; A61P25/22; A61P25/24; A61P25/28; A61P25/30; A61P25/32; A61P25/34; A61P25/36; A61P43/00; C07C231/12; C07C233/18; C07C269/06; C07C271/16; C07D209/08; C07D209/36; C07D209/38; C07D209/44; C07D215/20; C07D401/04; C07D401/06; C07D405/04; C07D405/06; C07D405/12
Domestic Patent References:
| JP53040766A |
Foreign References:
| US4129658 |
Other References:
國本雅也,かゆみの末梢神経機構,医学のあゆみ,2001年 5月26日,Vol.197 no.8,pp.591-594
Attorney, Agent or Firm:
Mitsuo Tanaka
Takuji Yamada
Mitsutaka Iwasaki
Aoyama Aoi
Takuji Yamada
Mitsutaka Iwasaki
Aoyama Aoi